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Old 03-04-2010, 03:40 AM   #8
Christine MH-UK
Senior Member
 
Join Date: Sep 2005
Posts: 414
Re: herceptin after chemo??

Yes, I have received it, but that was a while ago and the trend seems to be towards herceptin with chemo.

As far as I know, there was only one trial that compared herceptin after chemo with herceptin with chemo. Trial N9831 suggests that herceptin after chemo definitely improves disease-free survival (return of disease goes down by about 1/3). Herceptin with chemo though is considered to be even better since it reduces recurrence by another 1/4.

Here is the info on the trial, N9831:
http://www.abstracts2view.com/sabcs0...ABCS09L_992332

If any Her2-wonks are interested, here are some slides from Dr. Perez:
http://www.osuccc.osu.edu/SanAntonio/perez.pdf
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