HER2 Support Group Forums - View Single Post - FDA Approves Denosumab (Xgeva) for bone mets!

CourtneyL · 11-19-2010, 05:06 PM

Great news for us gals with bone mets - the FDA today approved Denosumab (brand name will be Xgeva) for cancers that have metastasized to the bones. According to my onc, Denosumab is a bigger better drug than Zometa - more effective, less side effects. It will be administered once a month in a shot to the arm.

So we're going to give it a roll and see how it goes! Stay tuned...

To read the FDA press release, visit:

http://www.fda.gov/NewsEvents/Newsro.../ucm234346.htm

11-19-2010, 05:06 PM	#1
CourtneyL Senior Member Join Date: Aug 2008 Location: San Francisco Posts: 260	FDA Approves Denosumab (Xgeva) for bone mets! Great news for us gals with bone mets - the FDA today approved Denosumab (brand name will be Xgeva) for cancers that have metastasized to the bones. According to my onc, Denosumab is a bigger better drug than Zometa - more effective, less side effects. It will be administered once a month in a shot to the arm. So we're going to give it a roll and see how it goes! Stay tuned... To read the FDA press release, visit: http://www.fda.gov/NewsEvents/Newsro.../ucm234346.htm __________________ 4/17/08: Dx Stage IV at age 30 - extensive mets to liver, lungs, and bones. Er/Pr-, Her2+++ April 08-Aug 08:Taxotere, Cytoxan, Herceptin, Zometa - complete response! Sept 08-Dec 08: Herceptin +Zometa for maintenance. Jan 09-April 09: Brain mets. Add Tykerb. Watch and wait. April 09: Gamma Knife 10 brain mets, add Xeloda. Sept 09: Gamma Knife to 1 brain met. Nov 09- April 10: Lung progression, add Gemzar to Herceptin, Zometa. May 10- Sept 10: HER2 Vaccine Trial Sept 10: Add Tykerb for more brain mets. Oct 10: Gamma Knife to 7 brain mets. Dec 10: Switch from Zometa to Denosumab. Jan 11: Gamma Knife to 3 brain mets. March 11: Gemzar/Herceptin for lung/bone progression. April 11: More brain mets - Intrathecal Herceptin June 11: Ixempra/Herceptin for lung, soft tissue progression. Aug 11: Gamma Knife Sep 11: Abraxane/Herceptin Future: NED Send me a PM if you'd like to follow my journey on Caringbridge.