HER2 Support Group Forums - View Single Post - Consumption of (n-3) Fatty Acids Is Related to Plasma Biomarkers of Inflammation and

03-13-2006, 06:18 PM

This is an interesting article.

As acknowledged reported food intake has it problems as a measuring device.

I wonder why they did not do tissue biopsies of blood, breast, waist and gluteal which would have given some indication of dietary consistency and a more accurate reflection of fat intake.

Other trials suggest increasing six over a certain point is a contributory negative factor.

The higher efficacy of fish oil over ALA is interesting 2.5.

Interesting they use CRP as a measure of inflamation.

Inflamation was reported as reduced. Trials have previously reported possible links between BC and inflamatory influences.

RB

http://www.nutrition.org/cgi/content/full/134/7/1806

ABSTRACT

In this study, we examined the relation between the intake of (n-3) fatty acids and plasma concentrations of biomarkers of inflammation and endothelial activation in apparently healthy women. Over the range of dietary intake in this population, we found an inverse relation between individual and total (n-3) fatty acids (ALA, EPA, and DHA) and plasma concentrations of CRP, IL-6, E-selectin, sICAM-1, and sVCAM-1. CRP levels were 29% lower among those in the highest quintile of total (n-3) fatty acid intake, compared with the lowest quintile; Il-6 levels were 23% lower, E-selectin 10% lower, sICAM-1 7% lower, and sVCAM-1 levels 8% lower. These associations were independent of lifestyle and dietary covariates and were not modified by intake of LA.

03-13-2006, 06:18 PM	#1
Unregistered Guest Posts: n/a	Consumption of (n-3) Fatty Acids Is Related to Plasma Biomarkers of Inflammation and This is an interesting article. As acknowledged reported food intake has it problems as a measuring device. I wonder why they did not do tissue biopsies of blood, breast, waist and gluteal which would have given some indication of dietary consistency and a more accurate reflection of fat intake. Other trials suggest increasing six over a certain point is a contributory negative factor. The higher efficacy of fish oil over ALA is interesting 2.5. Interesting they use CRP as a measure of inflamation. Inflamation was reported as reduced. Trials have previously reported possible links between BC and inflamatory influences. RB http://www.nutrition.org/cgi/content/full/134/7/1806 ABSTRACT In this study, we examined the relation between the intake of (n-3) fatty acids and plasma concentrations of biomarkers of inflammation and endothelial activation in apparently healthy women. Over the range of dietary intake in this population, we found an inverse relation between individual and total (n-3) fatty acids (ALA, EPA, and DHA) and plasma concentrations of CRP, IL-6, E-selectin, sICAM-1, and sVCAM-1. CRP levels were 29% lower among those in the highest quintile of total (n-3) fatty acid intake, compared with the lowest quintile; Il-6 levels were 23% lower, E-selectin 10% lower, sICAM-1 7% lower, and sVCAM-1 levels 8% lower. These associations were independent of lifestyle and dietary covariates and were not modified by intake of LA.