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Old 07-25-2014, 01:48 PM   #3
DizzyDo
Senior Member
 
Join Date: Feb 2014
Location: Washington State
Posts: 49
Re: Big news for Her2+!

There are also metastatic trials underway as well. Interesting that the stock for Puma (the biotech developing this) shot up 300% after this announcement. A lot of investors were shorting the stock (very common in biotech) because of the reports of diarrhea as a SE. LOL - almost all of our treatments do that!!!! I do the perjeta two step all the time. Also interesting that this might work better than herceptin. I wonder if it crosses the brain blood barrier? I think most nibs do. Looks like they are going for early approval, I wonder if it will be just for adjunct or also for metastatic.

Thanks for posting.
__________________
2009: dcis rt side, mastectomy, no chem or rads
2009: rt recon implant.
Jan 2014: stage 4. pain right side, found "too many to individually account for" liver mets. Found right axilla lymph nodes and nearby mass (source). Lung, lymph and bone mets. Brain clear by MRI. Er and pr neg, HER2 +++
Feb 2014: herceptin, perjeta, taxol
July 2014: no active disease, only bone scars and 1 liver scar! Tumor markers all normal again.
Dec 2014: seizure, 3 brain mets (15, 5 and 3 mm)
Feb 2015: Linac Stereotactic Radiation for brain mets
June 2015: no new brain mets, old ones greatly reduced in size. Bod still no active disease
October 2015: New brain Met, zapped by Stereotactic rads, watching another spot
Jan 2016: The other spot grew, zapped again. Still on herceptin and perjeta every 3 weeks
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