[carolanno]

in a study comparing taxol/Herceptin w/Taxol/herceptin/Perjeta, the latter group had more diarrhea so the addition of perjeta did cause more GI effects. i had diarrhea i week after my loading dose of perjeta which is twice the subsequent infusions. i have not had any problems since on herceptin/perjeta. Maybe you'll be ok next time.I have a sensitive stomach too, but have not had any nausea. hope it improves!