HER2 Support Group Forums - View Single Post - Scientists find cause of reduced drug sensitivity in HER2-positive breast cancer

News · 10-13-2015, 04:23 AM

In the presence of the HER2 inhibitor lapatinib, the tumor suppressor molecule FOXO changes role and desensitizes HER2+ breast cancer cells to the drug, leading to relapse.

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10-13-2015, 04:23 AM	#1
News Senior Member Join Date: Oct 2007 Posts: 18,957	Scientists find cause of reduced drug sensitivity in HER2-positive breast cancer In the presence of the HER2 inhibitor lapatinib, the tumor suppressor molecule FOXO changes role and desensitizes HER2+ breast cancer cells to the drug, leading to relapse. More...