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Recurrence rate after 5 years for ER+/PR-/HER-2+?
Hi HER-2ers,
Last Friday I learned of a fellow BC survivor who just found out her cancer recurred in her bones and liver at full speed. She was diagnosed shortly after me while and is 5 years out. Her tumor was ER+/PR+/HER-2-. I know estrogen fueled tumors can recur between years 5-10 at a higher likelihood than us HEr-2+ folks. But how about when your tumor is mostly HER-2, PR- and only 30% ER+? Does the recurrence pattern follow that of ER+/HER-2- tumors or is more aligned with the HER-2+/ER- ones? That is, how anxious should I be now that I am 5 years out? My friend's news has left me sad for her and her family and worried about me. Can anyone comment on the latest and greatest HER-2 recurrence rate knowledge?
Thanks!!!
Bejuce
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ER+ (30%)/PR-/HER-2+, stage 3
Diagnosed on 02/18/09 at 38 with a huge 12x10 cm tumor, after a 6 month delay. Told I was too young and had no risk factors. Found swollen node during breastfeeding.
March-August 09: neo-adjuvant chemo, part of a trial at Stanford (4 DD A/C, 4 Taxotere with daily Tykerb), loading dose of Herceptin
08/12/09 - bye bye boobies (bilateral mastectomy)
08/24/09 - path report shows 100 % success in breast tissue (no cancer there, yay!), 98 % success in lymphatic invasion, and even though 11/13 nodes were still positive, > 95 % of the tumor in them was killed. Hoping for the best!
September-October 09: rads with daily Xeloda
02/25/10 - Cholecystectomy
05/27/10 - Bone scan clear
06/14/10 - CT scan clear, ovarian cyst found
07/27/10 - Done with Herceptin!
02/15/11 - MVA-BN HER-2 vaccine trial
03/15/11 - First CA 15-3: 12.7 and normal, yay!
10/01/11 - Bone scan and CT scan clear, fatty liver found
now on Tamoxifen and Aspirin
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