HER2 Support Group Forums - View Single Post - Vitamin D thread -Please use this for your Vit D info.

R.B. · 01-01-2016, 03:40 PM

http://www.ncbi.nlm.nih.gov/pubmed/26554935

Low Vit D and triple negative

ABSTRACT

J Steroid Biochem Mol Biol. 2015 Nov 7. pii: S0960-0760(15)30129-1. doi: 10.1016/j.jsbmb.2015.11.003. [Epub ahead of print]
Vitamin D levels and breast cancer characteristics: Findings in patients from Saudi Arabia.
Abulkhair O1, Saadeddin A1, Makram O1, Gasmelseed A1, Pasha T1, Shehata H1, Fakhoury HM2.
Author information
Abstract

Inverse relationship between vitamin D status and risk of breast cancer has been previously reported in the literature. We conducted this study to determine the association between vitamin D levels and breast cancer characteristics in patients from Saudi Arabia. Newly diagnosed breast cancer patients (N=406) were recruited. Serum levels of 25-hydroxyvitamin D [25 (OH) D] were measured at baseline. A significantly higher percentage of patients with triple negative status (18%) had 25 (OH) D levels ≤25nmol/L, compared to only 8% with 25 (OH) D levels >25nmol/L (p=0.009). Patients with 25 (OH) D levels ≤25nmol/L were 2.54 times more likely to present with triple negative status compared to those with 25 (OH) D levels >25nmol/L (p=0.02). Our findings suggest an association between low 25 (OH) D levels and increased risk of triple negative breast cancer.

Copyright © 2015 Elsevier Ltd. All rights reserved.

01-01-2016, 03:40 PM	#72
R.B. Senior Member Join Date: Mar 2006 Posts: 1,843	Re: Vitamin D thread -Please use this for your Vit D info. http://www.ncbi.nlm.nih.gov/pubmed/26554935 Low Vit D and triple negative ABSTRACT J Steroid Biochem Mol Biol. 2015 Nov 7. pii: S0960-0760(15)30129-1. doi: 10.1016/j.jsbmb.2015.11.003. [Epub ahead of print] Vitamin D levels and breast cancer characteristics: Findings in patients from Saudi Arabia. Abulkhair O1, Saadeddin A1, Makram O1, Gasmelseed A1, Pasha T1, Shehata H1, Fakhoury HM2. Author information Abstract Inverse relationship between vitamin D status and risk of breast cancer has been previously reported in the literature. We conducted this study to determine the association between vitamin D levels and breast cancer characteristics in patients from Saudi Arabia. Newly diagnosed breast cancer patients (N=406) were recruited. Serum levels of 25-hydroxyvitamin D [25 (OH) D] were measured at baseline. A significantly higher percentage of patients with triple negative status (18%) had 25 (OH) D levels ≤25nmol/L, compared to only 8% with 25 (OH) D levels >25nmol/L (p=0.009). Patients with 25 (OH) D levels ≤25nmol/L were 2.54 times more likely to present with triple negative status compared to those with 25 (OH) D levels >25nmol/L (p=0.02). Our findings suggest an association between low 25 (OH) D levels and increased risk of triple negative breast cancer. Copyright © 2015 Elsevier Ltd. All rights reserved.