HER2 Support Group Forums - View Single Post - turning the wrong switch with inflammation fuels cancer and...

heblaj01 · 03-02-2007, 08:54 AM

The findings described in the previous posts about the role of inflammation in cancer, brings up in my mind one of the possible related roles of vitamin D3 in regulating the immune system from over or under stimulation.

For instance preclinical studies have shown that vitamin D3 fights autoimmune diseases & one clinical trial has been verifying its effects on rhumatoid arthritis (which incidentally has been found associated with greater incidence of cancer):
http://clinicaltrials.gov/ct/gui/sho...25714?order=42
Vitamin D Deficiency Causes Immune Dysfunction and Enables or Perpetuates the Development of Rheumatoid Arthritis

http://www.blackwell-synergy.com/lin....01204.x/full/
Identification and immune regulation of 25-hydroxyvitamin D-1-α-hydroxylase
in murine macrophages

This indirect role of vitamin D on inflammation would be one of its other modes of action
which are claimed to provide protection against cancer as evidenced by the statitics published last year.

03-02-2007, 08:54 AM	#7
heblaj01 Senior Member Join Date: Apr 2006 Posts: 543	The findings described in the previous posts about the role of inflammation in cancer, brings up in my mind one of the possible related roles of vitamin D3 in regulating the immune system from over or under stimulation. For instance preclinical studies have shown that vitamin D3 fights autoimmune diseases & one clinical trial has been verifying its effects on rhumatoid arthritis (which incidentally has been found associated with greater incidence of cancer): http://clinicaltrials.gov/ct/gui/sho...25714?order=42 Vitamin D Deficiency Causes Immune Dysfunction and Enables or Perpetuates the Development of Rheumatoid Arthritis http://www.blackwell-synergy.com/lin....01204.x/full/ Identification and immune regulation of 25-hydroxyvitamin D-1-α-hydroxylase in murine macrophages This indirect role of vitamin D on inflammation would be one of its other modes of action which are claimed to provide protection against cancer as evidenced by the statitics published last year.