That was worth the lengthy read if only to come across "diabetes insipidus"
Regarding Lani's input, I have to say the bone/bone marrow to mets link issue seems to be a repeating issue in cancer stem cell viewpoint. If it doesn't interfere with your overall plan, you might consider moving your Zometa to around 24 hrs after whatever other infusion you get. There is suggestion following chemo with Zometa can synergize the two. Me thinks (armchair onc) by drawing the chemo to the bone tissue/marrow where met signals may be formulated. Have you considered Cellsearch or serum her2 test?
Oh..another highlight: "infindibulum" Just damn fun to say.