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donocco · 10-01-2020, 12:36 PM

Laurel

If you are not Tamoxifen Im curious if you are on any antidepressant medications for hot flashes. If you are, you have to be careful which one has been prescribed. Tamoxifen is metabolized by the liver enzyme CYP2D6 to its active form. many of the common antidepressants such as Fluoxetine (Prozac)
Paroxetine (Paxil) Bupropion (Wellbutrin) and Cymbalta inhibit the CYP2D6 enzyme. I think you can use Effexor and Celexa with Tamoxifen. Id have to check.

Paul

10-01-2020, 12:36 PM	#11
donocco Senior Member Join Date: Oct 2013 Posts: 474	Re: It's Been Awhile Laurel If you are not Tamoxifen Im curious if you are on any antidepressant medications for hot flashes. If you are, you have to be careful which one has been prescribed. Tamoxifen is metabolized by the liver enzyme CYP2D6 to its active form. many of the common antidepressants such as Fluoxetine (Prozac) Paroxetine (Paxil) Bupropion (Wellbutrin) and Cymbalta inhibit the CYP2D6 enzyme. I think you can use Effexor and Celexa with Tamoxifen. Id have to check. Paul