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Old 10-21-2014, 10:09 PM   #8
Pamelamary
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Join Date: Apr 2012
Location: Melbourne, Australia
Posts: 494
Re: Liver mets....advice?

Dear Embur,
I know liver mets sound scary, but there are numbers of women on this site who have had good results from treatment. Mine actually appeared while on a trial with TDM-1, but Docetaxol and Herceptin shrank the nasty little critters almost completely. I am still stable and living well on Herceptin and Tamoxifen, hoping to emulate some of our sisters with 10 years or more at Stage IV.
Just remember we are all different and there are many treatment options available. I hope you and your onc quickly settle on a treatment plan that is effective and not too onerous.
Sending best wishes..... Pam
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Diagnosed 2004: Lumpectomy - 2 tumours, both grade 1 infiltrating duct carcinoma, about 12mm. ER+,
C-erbB-2 status 3+.
Clear margins, no nodal involvement.
Radiotherapy, i year Tamoxifen, 4 years Arimidex.
Rediagnosed 2012: Multiple bone metastases.
3/12: began on Marianne trial - T-DM1 + Pertuzamab/Placebo.
5/12:Unexpected development of numerous bilateral liver mets. Came off trial.
Started Docetaxol/ Herceptin + Zometa.
8/12:Bones stable +major regression in liver (!)
9/12:Can't take any more Docetaxol! Start on Herceptin and Tamoxifen. Cross fingers!
Changed to Denosumab.
11/12: Scan shows stable - yay!
11/13: Still stable :-) !!!
1/16: All stable, but lowered calcium, so switched to Zometa 3 monthly.
2/19: Happily still stable on Herceptin, Letrozole and 3 monthly Zometa.
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