[chrisy]

Brenda, you spoke very well for me. I invite you to speak for me whenever you want!!!!!

Yes, the last shoe reference was to the long road to determining progression on TDM1, which actually started in December!

Sorry I have not posted any responses to anyone, I have been travelling around all week and only have my iphone which has it's own ideas about how to respond to keystrokes!

I am, as Brenda said, in the process of screening for this new study, one criteria I can check off is the LVEF which came back a nice strong 66. A few of the other criteria are dicey, and I'm waiting to hear back re the screening blood labs I had drawn yesterday.

I am planning to have a new liver biopsy - I think it was Becky it the nail on the head, my Dr. is wondering if maybe now there is some ER/PR positivity.

On the other point, research on linking a different chemo to herceptin, there is research ongoing on that question. I do remember speaking with the genentech researcher who developed TDM1 who told me they had experimented with many many different agents during TDM1 development - like everything else, it is always more complicated than we'd like.

Now that I am back on a real computer, I'll reread all the comments - lots of great things to think about, thank you!