HER2 Support Group Forums - View Single Post - Results of Utility of Long-term Herceptin Use After Adjuvant Chemotherapy

Barbara2 · 03-09-2011, 07:19 AM

http://www.cancernetwork.com/practic.../10165/1816904

Overall, the study shows that Herceptin is efficacious as an adjuvant treatment. Nevertheless, the result that extending the period between chemotherapy and the start of Herceptin to 1 to 3 years has a benefit for early breast cancer patients will need to be followed up with a controlled, randomized clinical trial. The optimal Herceptin duration of treatment is still not known and is the subject of ongoing clinical trials. Furthermore, as the author of the accompanying editorial mention, a 4-year follow up is still quite short for an adjuvant trial and it may still play out that concurrent chemotherapy and Herceptin treatment is a more effective strategy that chemotherapy followed by Herceptin in an adjuvant setting.

03-09-2011, 07:19 AM	#1
Barbara2 Senior Member Join Date: Sep 2005 Location: South Dakota. Posts: 621	Results of Utility of Long-term Herceptin Use After Adjuvant Chemotherapy http://www.cancernetwork.com/practic.../10165/1816904 Overall, the study shows that Herceptin is efficacious as an adjuvant treatment. Nevertheless, the result that extending the period between chemotherapy and the start of Herceptin to 1 to 3 years has a benefit for early breast cancer patients will need to be followed up with a controlled, randomized clinical trial. The optimal Herceptin duration of treatment is still not known and is the subject of ongoing clinical trials. Furthermore, as the author of the accompanying editorial mention, a 4-year follow up is still quite short for an adjuvant trial and it may still play out that concurrent chemotherapy and Herceptin treatment is a more effective strategy that chemotherapy followed by Herceptin in an adjuvant setting. __________________ Blessings and Peace, Barbara DX Oct 02 @ age 52 Stage 2B Grade 3 Mastectomy "at least" 4.5 cm IDC 1+node ER+61% /PR- Assiciated Intraductual component with Comedo Necrosis Her2+ FISH8.6 IHC 2+ 5 1/2 CEF Arimidex Celebrex 400mg daily for 13 months Prophylactic mastectomy Estradiol #: 13 PTEN positive, "late" Herceptin (26 months after chemo) Oct 05: Actonel for osteopenia from Arimidex. May 08: Replaced Actonel with Zometa . Taking every 6 months. Accepting the gift of life, I give thanks for it and live it in fullness.