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Re: On to next combo--H,P and ???
Amy,
You are totally correct about the tissue damage caused by some chemos, they are called vesicants. And they administer them very slowly and ask if you feel any pain while the meds are administered. Don't let any one bully you into a port, if you read my signature, you'll see I've been on my share of chemos, gemzar burned going in, epirubicin, carboplatin, all while getting an i.v. started each time in my hand or arm. No ports for this girl.
And to give you some confidence in the P/H combo, I was started on P/H and taxotere and had to stop the taxotere after 3 months due to side effects and my insurance has been happy to keep me on the P/H combo ever since. 
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[B]Kristin
Aug 2010: diagnosed stage 3b, 4 mo. after birth of son. 29 yrs old and breastfeeding, ER/PR-, Her-2+ started Neoadjuvant therapy: 4x FEC, 10x abraxane & Herceptin
Feb 2011: L mx with recon. Path. showed only DCIS but 4/10+ nodes.
March 2011: 6 wks rads.
Mother passed, lower back pain.
Late May 2011: Bone mets but organs clear; Tykerb, Xeloda, Xgeva. Stopped Herceptin. Implant infected: removed implant.
October 2011: Bone progression; Gemzar and Carboplatin & restarted Herceptin.
Jan 2012: Progression, re-classified as ER+; Tykerb, Herceptin, Zoladex & Femara. Anti-E is working!
May 2012: ovaries out, markers stable but elevated. Cont. Herceptin, Tykerb, Xgeva & Femara.
Dec 2012: aromasin
Jan 2013: faslodex, herceptin, tykerb
Jun: Kadcyla
Aug: Rads to hip, then Perjeta, Herceptin & Taxotere
Nov 2013: Perjeta, Herceptin, Halaven
Early 2014: Affinitor, Aromasin, Perjeta, Herceptin.
June 2014: Estradiol, Perjeta, Herceptin
Aug 14: Tamoxofin, H & P
http://kristin-notdying-blog.blogspot.com/
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