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Re: On to next combo--H,P and ???
Amy,
I feel your pain, I am also stage IV without a port and want to avoid one for as long as possible. I have great veins and my onc has never mentioned needing one for any reason, he sees them as more of an infection risk (couldn't agree more, as my tissue expander gave me cellulitis and I lost it only a few weeks after I completed radiation therapy). Kadcyla was also short lived with me, I never really had a + response, only stable disease for a few months. Have you tried Halaven? I'm currently on that one, but am looking forward to getting off it as it's given me bad neuropathy in my feet and ankles.
I am wondering what are the next "sexy" new drug combos after Kadcyla and perjeta, speaking of which you should totally get on perjeta, it is so easy and biochemically superior to herceptin and Kadcyla. Best wishes.
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[B]Kristin
Aug 2010: diagnosed stage 3b, 4 mo. after birth of son. 29 yrs old and breastfeeding, ER/PR-, Her-2+ started Neoadjuvant therapy: 4x FEC, 10x abraxane & Herceptin
Feb 2011: L mx with recon. Path. showed only DCIS but 4/10+ nodes.
March 2011: 6 wks rads.
Mother passed, lower back pain.
Late May 2011: Bone mets but organs clear; Tykerb, Xeloda, Xgeva. Stopped Herceptin. Implant infected: removed implant.
October 2011: Bone progression; Gemzar and Carboplatin & restarted Herceptin.
Jan 2012: Progression, re-classified as ER+; Tykerb, Herceptin, Zoladex & Femara. Anti-E is working!
May 2012: ovaries out, markers stable but elevated. Cont. Herceptin, Tykerb, Xgeva & Femara.
Dec 2012: aromasin
Jan 2013: faslodex, herceptin, tykerb
Jun: Kadcyla
Aug: Rads to hip, then Perjeta, Herceptin & Taxotere
Nov 2013: Perjeta, Herceptin, Halaven
Early 2014: Affinitor, Aromasin, Perjeta, Herceptin.
June 2014: Estradiol, Perjeta, Herceptin
Aug 14: Tamoxofin, H & P
http://kristin-notdying-blog.blogspot.com/
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