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Mandamoo · 10-27-2011, 04:31 AM

I'm so sorry to hear that Trish - I hope that the New York vibe is better than any chemo thrown at those mets! We were there at Xmas time and had the most fabulous time. I imagine that Central Park will be amazing in Fall.
I am going OK with the treatment - I am not seeing much reduction in my skin met but I had reduction in my axilla node and my lungs were stable (there was maybe a little growth but too small to tell). Next scan in a couple of weeks. We are pretty sure I am on the Everolimus as I had throat ulcers and neutropenia that ended me in hospital - so dose was reduced. The ulcers are a very common side effect of the everolimus. I still get them every now and again on the reduced dose. I guess we don't know for sure though. I also had some nose bleeding which again is a possible side effect of the Everolimus. My onc is very excited about everolimus - especially since the Bolero 2 trial has been halted as the interim results were so successful.
Would Novartis consider compassionate funding for you?
Enjoy New York, New York.
Amandaxx

10-27-2011, 04:31 AM	#16
Mandamoo Senior Member Join Date: Jul 2011 Location: Melbourne, Australia Posts: 432	Re: Australian Treatments and Access I'm so sorry to hear that Trish - I hope that the New York vibe is better than any chemo thrown at those mets! We were there at Xmas time and had the most fabulous time. I imagine that Central Park will be amazing in Fall. I am going OK with the treatment - I am not seeing much reduction in my skin met but I had reduction in my axilla node and my lungs were stable (there was maybe a little growth but too small to tell). Next scan in a couple of weeks. We are pretty sure I am on the Everolimus as I had throat ulcers and neutropenia that ended me in hospital - so dose was reduced. The ulcers are a very common side effect of the everolimus. I still get them every now and again on the reduced dose. I guess we don't know for sure though. I also had some nose bleeding which again is a possible side effect of the Everolimus. My onc is very excited about everolimus - especially since the Bolero 2 trial has been halted as the interim results were so successful. Would Novartis consider compassionate funding for you? Enjoy New York, New York. Amandaxx __________________ Amanda xx 40 year old Mum to three gorgeous kids - son 5 and daughters 8 and 11 Wife to my wonderfully supportive husband of 17 years! 22 February 2011 - Diagnosed Early Breast Cancer IDBC Stage2b (ER/PR -ve, Her2+ve +++) - 38 years old (L) skin sparing mastectomy with tissue expander, axilla clearance (2/14 affected) clear margins. Fec3, Taxotere and herceptin2 - stopped due to secondary diagnosis June 24 2011 Stage IV - Skin met, axilla node, multiple lung lesions Bolero3 trial - Navelbine, Hereptin weekly, daily Everolimus/Placebo February 2012 - July 2012 Tykerb and Xeloda - skin mets resolved, Lungs initially dramatically reduced but growing again August 2012 (turn 40!) tykerb and herceptin (denied compassionate use of TDM1) while holidaying in Italy! September 2012 - January 2013 TDM1 as part of the Th3resa trial - lymph nodes resolved, lungs slowly progressing. January 2013 - herceptin, carboplatin and Perjeta (compassionate access) April 2013 - Some progression in lungs and lymph nodes - Abraxane, Herceptin and Perjeta July 2013 - mixed response - dramatic reduction of most lung disease, progression of smaller lung nodules and cervical and hilar nodes - ? Add avastin.