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Laurie7 · 05-29-2012, 09:10 PM

Hi All!

I have been on T-DM1 since July 2011...so far things are STABLE! Hoping they stay this way! (Although a little shrinkage wouldn't be so bad either lol)..I too have had low platelets and elevated liver enzymes...and frequents nose bleeds (which is just annoying, but I can definatly live with them) I had two dose reductions because of the liver enzymes (I think that's my limit) So I'm really hoping and praying that it continues to work for me I go for my 6 week scan this Friday so time will tell! Does anyone experience achy/stiffening of their feet/heels/calves after resting/sleeping?? But once I am up and moving it goes away.. I'm trying to determine if its my meds or just age (although it's much more noticeable and constant in the past few months). I am also on Ixgeva(Denosumab) for my bones, is anyone else on this and if so, do you have these symptoms??

Laurie

05-29-2012, 09:10 PM	#14
Laurie7 Member Join Date: Jul 2011 Location: Pingree Grove, Il Posts: 15	Re: Anyone on TDM1??? Hi All! I have been on T-DM1 since July 2011...so far things are STABLE! Hoping they stay this way! (Although a little shrinkage wouldn't be so bad either lol)..I too have had low platelets and elevated liver enzymes...and frequents nose bleeds (which is just annoying, but I can definatly live with them) I had two dose reductions because of the liver enzymes (I think that's my limit) So I'm really hoping and praying that it continues to work for me I go for my 6 week scan this Friday so time will tell! Does anyone experience achy/stiffening of their feet/heels/calves after resting/sleeping?? But once I am up and moving it goes away.. I'm trying to determine if its my meds or just age (although it's much more noticeable and constant in the past few months). I am also on Ixgeva(Denosumab) for my bones, is anyone else on this and if so, do you have these symptoms?? Laurie __________________ Laurie :) 2006..Dx w Stage1 DCIS age32 Had lft breast mastectomy -4 cycles A/C 12wks..4 cycles Taxol/Herceptin 12 wks (herceptin 1yr total) 2007..prophylactic rt breast mastectomy *May2011..was told I was CURED & within 2 days was reDX w stageIV mets to my liver,lungs,&bone -6wks Herceptin(little progression to liver) -started clinical trial on July 19th T-DM1....Hopeful!