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Old 10-12-2008, 07:35 AM   #5
hutchibk
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hmmm - I would 1. talk to the insurance/business office person at the doctor's office, and also 2. call your ins company to confirm, and 3. also consider changing oncologists. One thing to know is that it is not unheard of for an unsavory oncologist to "steer" you towards treatments that they make more money from. A cynical view, I know, but I have heard that it does happen. Also, maybe post your question on the main forum here... the general her2 forum.

I found this Q and A on the Breastcancer.org website... doesn't speak to insurance coverage, though.

Study with AI plus Herceptin, no chemo?

Question from Rooster: I'm post-menopausal, hormone-receptor-positive, HER2-positive breast cancer. I want the benefits of hormonal therapy and Herceptin—but I'd really like to avoid chemo. I heard about a study using an aromatase inhibitor along with Herceptin, without the chemo. Tell me more about this?
Answer —Jennifer Griggs, M.D., M.P.H.: It sounds as if the tumor that you've been treated for is responsive both to hormonal therapies and to Herceptin. Most U.S. oncologists have favored chemotherapy in patients whose tumors are HER2-positive. The use of hormonal therapy and Herceptin without chemotherapy is particularly appealing in somebody with an otherwise "lower risk" tumor, for example, small tumor, negative nodes. The benefits of chemotherapy may be small in somebody with a small tumor and negative lymph nodes. Nonetheless, as I said above, most oncologists will recommend chemotherapy in this setting. This is something you'll want to talk about with your doctor in your particular case. At the San Antonio conference, the combination of an aromatase inhibitor and Herceptin was shown to be highly effective in women with advanced, metastatic breast cancer. Most of us who take care of patients have used this combination for quite some time, often with long-lasting results. Studying this combination without chemotherapy in women with early stage disease will be important before it becomes standard practice.
__________________
Brenda

NOV 2012 - 9 yr anniversary
JULY 2012 - 7 yr anniversary stage IV (of 50...)

Nov'03~ dX stage 2B
Dec'03~
Rt side mastectomy, Her2+, ER/PR+, 10 nodes out, one node positive
Jan'04~
Taxotere/Adria/Cytoxan x 6, NED, no Rads, Tamox. 1 year, Arimadex 3 mo., NED 14 mo.
Sept'05~
micro mets lungs/chest nodes/underarm node, Switched to Aromasin, T/C/H x 7, NED 6 months - Herceptin only
Aug'06~
micro mets chest nodes, & bone spot @ C3 neck, Added Taxol to Herceptin
Feb'07~ Genetic testing, BRCA 1&2 neg

Apr'07~
MRI - two 9mm brain mets & 5 punctates, new left chest met, & small increase of bone spot C3 neck, Stopped Aromasin
May'07~
Started Tykerb/Xeloda, no WBR for now
June'07~
MRI - stable brain mets, no new mets, 9mm spots less enhanced, CA15.3 down 45.5 to 9.3 in 10 wks, Ty/Xel working magic!
Aug'07~
MRI - brain mets shrunk half, NO NEW BRAIN METS!!, TMs stable @ 9.2
Oct'07~
PET/CT & MRI show NED
Apr'08~
scans still show NED in the head, small bone spot on right iliac crest (rear pelvic bone)
Sept'08~
MRI shows activity in brain mets, completed 5 fractions/5 consecutive days of IMRT to zap the pesky buggers
Oct'08~
dropped Xeloda, switched to tri-weekly Herceptin in combo with Tykerb, extend to tri-monthly Zometa infusion
Dec'08~
Brain MRI- 4 spots reduced to punctate size, large spot shrunk by 3mm, CT of torso clear/pelvis spot stable
June'09~
new 3-4mm left cerrebellar spot zapped with IMRT targeted rads
Sept'09~
new 6mm & 1 cm spots in pituitary/optic chiasm area. Rx= 25 days of 3D conformal fractionated targeted IMRT to the tumors.
Oct'09~
25 days of low dose 3D conformal fractionated targeted IMRT to the bone mets spot on rt. iliac crest that have been watching for 2 years. Added daily Aromasin back into treatment regimen.
Apr'10~ Brain MRI clear! But, see new small spot on adrenal gland. Change from Aromasin back to Tamoxifen.
June'10~ Tumor markers (CA15.3) dropped from 37 to 23 after one month on Tamoxifen. Continue to monitor adrenal gland spot. Remain on Tykerb/Herceptin/Tamoxifen.
Nov'10~ Radiate positive mediastinal node that was pressing on recurrent laryngeal nerve, causing paralyzed larynx and a funny voice.
Jan'11~ MRI shows possible activity or perhaps just scar tissue/necrotic increase on 3 previously treated brain spots and a pituitary spot. 5 days of IMRT on 4 spots.
Feb'11~ Enrolled in T-DM1 EAP in Denver, first treatment March 25, 2011.
Mar'11~ Finally started T-DM1 EAP in Denver at Rocky Mountain Cancer Center/Rose on Mar. 25... hallelujah.

"I would rather be anecdotally alive than statistically dead."
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