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Gotta say...
Mom was Dx late '04 HER2 + ER+. Docs recommended rads and Arimidex. I got her numerous 2nd opinions..all went with original doc. Trials were available but they thought chemo too harsh. I argued for Herceptin alone with no takers. Also argued for Oncotype DX test to evaluate risk vs benefit better..no takers. After radiologist told her she had a "cured cancer", Mom now has mets in liver and lungs. At this point, the cancer stem cell issue or paradigm shift feels like Herceptin did back then: New, likely a game changer, and largely ignored outside of trials.
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