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Hi Elaine,
I stopped Herceptin/Gemzar earlier this month in preparation for Tykerb/Abraxane(had Xeloda with Herceptin for a year just prior to Gemzar). The plan is for Abraxane weekly along with the daily Tykerb; I had my first Abraxane infusion last week and am just waiting for the Tykerb process to be completed to add it. So far no side effects from Abraxane except tiredness. Hair loss can happen by the second week, so we'll see...
My onc did some research and called a mentor in the research field to settle on Abraxane for me, given my history of prior sequential chemo's: Navelbine 3 separate times, Xeloda, then Gemzar.
Hope this helps, check the board for others Tykerb side effects some of which are related to Xeloda.
<3 Lolly
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Sept.'99 - Dx.Stage IIIB, IDC ER/PR-, HER2+++ by IHC, confirmed '04 by FISH. Left MRM, AC x's 4, Taxol x's 4, 33 Rads, finishing Tx May 2000. Jan.'01 - local/regional recurrence, Stage IV. Herceptin/Navelbine weekly till NED August 2001, then maintenance Herceptin. Right Mast. April 2002. Local/Regional recurrence April '04, Herceptin plus/minus chemo until May '07. Gemzar added from Feb.'07-April '07; Tykerb/Abraxane until August '07, back on Herceptin plus Taxotere and Xeloda Sept. '07. Stopped T/X Nov. '07, stopped Herceptin Dec. '07, started Avastin/Taxol/Carboplatin Dec. '07. Progression in chest skin, stopped TAC March '03, started radiation.
Herceptin has served as the "Backbone" of my treatment strategy for over 6 years, giving me great quality of life. In 2005, I was privileged to participate in the University of Washington/Seattle HER2 Vaccine Trial.
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