Thread: estrogen creams
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Old 07-26-2007, 09:19 AM   #20
hutchibk
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I attended an MDAnderson Living Fully With & Beyond Cancer Conference last Sept. This was a subject that was covered in one of the Breast Cancer break-out sessions. We talked pretty in depth about a few things to do to recover from atrophy and loss of sensation. Here's what I learned, but have yet to fully implement... but I plan to.

First, one thing my Gyn told me early on was to "continue to have sex after chemo induced menopause, even when you don't feel like it" - my partner was thrilled to hear her say this and he asked if she could write a prescription stating that. LOL. She said that continuing sex would be the best way to keep the vagina in shape and avoid atrophy. Well, that didn't happen in my world, as I am sure it doesn't happen in the lives of many of us.

I also learned... get this...I did not know this...that Taxol can also cause numbness and neuropathy not only in the hands and feet, but guess where else? Boy was I happy to learn that and know that it should self correct for the most part once I was done with Taxol.

So, I learned a "get back in shape plan" at the conference last year. Basically they suggested that we have to take this on as we would a training program.

First, talk to your doctor about using an estrogen cream or medication (Estrace, Estring, Premarin {which personally I don't like because of what it's made from and problems from it... google it}) Check this site for good info about using the creams: http://www.mayoclinic.com/health/dru...ation/DR202227
My onc does not feel that Estrace is strong enough percentage wise to have a systemic effect. Ask your doc about this before you proceed.

Second, acquire a good lubricant and a "personal massager." They suggested that using the cream and gently using the massager a couple to a few times a week in conjunction with the estrogen would slowly toughen and build back the vaginal walls, decrease pain and increase sensation. It might take several weeks or a few months to feel noticible results, but basically it is a training program for the female parts. Put yourself in training, they said. We all had a great laugh at that, but it made sense.

Third, slowly add in a "real partner" as you see fit and reap the benefits of your training...

I personally have used Estrace cream for a couple of years to stem the recurrance of UTIs and it has worked very well for me in mitigating the UTIs and restoring sensation. The UTIs were caused by dry, sensitive urinary track tissue being irritated to the point of infection by different caustic chemo drugs on their way out of the body. I also saw a urologist who echoed this and agreed with our plan.
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Brenda

NOV 2012 - 9 yr anniversary
JULY 2012 - 7 yr anniversary stage IV (of 50...)

Nov'03~ dX stage 2B
Dec'03~
Rt side mastectomy, Her2+, ER/PR+, 10 nodes out, one node positive
Jan'04~
Taxotere/Adria/Cytoxan x 6, NED, no Rads, Tamox. 1 year, Arimadex 3 mo., NED 14 mo.
Sept'05~
micro mets lungs/chest nodes/underarm node, Switched to Aromasin, T/C/H x 7, NED 6 months - Herceptin only
Aug'06~
micro mets chest nodes, & bone spot @ C3 neck, Added Taxol to Herceptin
Feb'07~ Genetic testing, BRCA 1&2 neg

Apr'07~
MRI - two 9mm brain mets & 5 punctates, new left chest met, & small increase of bone spot C3 neck, Stopped Aromasin
May'07~
Started Tykerb/Xeloda, no WBR for now
June'07~
MRI - stable brain mets, no new mets, 9mm spots less enhanced, CA15.3 down 45.5 to 9.3 in 10 wks, Ty/Xel working magic!
Aug'07~
MRI - brain mets shrunk half, NO NEW BRAIN METS!!, TMs stable @ 9.2
Oct'07~
PET/CT & MRI show NED
Apr'08~
scans still show NED in the head, small bone spot on right iliac crest (rear pelvic bone)
Sept'08~
MRI shows activity in brain mets, completed 5 fractions/5 consecutive days of IMRT to zap the pesky buggers
Oct'08~
dropped Xeloda, switched to tri-weekly Herceptin in combo with Tykerb, extend to tri-monthly Zometa infusion
Dec'08~
Brain MRI- 4 spots reduced to punctate size, large spot shrunk by 3mm, CT of torso clear/pelvis spot stable
June'09~
new 3-4mm left cerrebellar spot zapped with IMRT targeted rads
Sept'09~
new 6mm & 1 cm spots in pituitary/optic chiasm area. Rx= 25 days of 3D conformal fractionated targeted IMRT to the tumors.
Oct'09~
25 days of low dose 3D conformal fractionated targeted IMRT to the bone mets spot on rt. iliac crest that have been watching for 2 years. Added daily Aromasin back into treatment regimen.
Apr'10~ Brain MRI clear! But, see new small spot on adrenal gland. Change from Aromasin back to Tamoxifen.
June'10~ Tumor markers (CA15.3) dropped from 37 to 23 after one month on Tamoxifen. Continue to monitor adrenal gland spot. Remain on Tykerb/Herceptin/Tamoxifen.
Nov'10~ Radiate positive mediastinal node that was pressing on recurrent laryngeal nerve, causing paralyzed larynx and a funny voice.
Jan'11~ MRI shows possible activity or perhaps just scar tissue/necrotic increase on 3 previously treated brain spots and a pituitary spot. 5 days of IMRT on 4 spots.
Feb'11~ Enrolled in T-DM1 EAP in Denver, first treatment March 25, 2011.
Mar'11~ Finally started T-DM1 EAP in Denver at Rocky Mountain Cancer Center/Rose on Mar. 25... hallelujah.

"I would rather be anecdotally alive than statistically dead."
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