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Well..not sure where the data is coming from, but Dr. Pegram worked with Dr. Slaman on the development of Herceptin, and is known as one of the top researchers in the country.
If he says it, that's good enough for me. However, next time I see him I will ask him. From my understanding the toxicity was only associated with the 30 min infusion on the every 3 weeks schedule. When they went to a 90 min infusion rate, the cardio-toxity problems disappeared.
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