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Mtngrl · 09-03-2016, 07:13 AM

Joan--

My oncologist recommended the test that Guardant does. (http://guardanthealth.com/). It tests circulating tumor cells and identifies mutations and amplifications.

My test showed three mutations and three amplifications. One of my amplifications is HER-2 (of course!). One of the mutations is P-53. There are drugs in phase 1 clinical trials for several of the abnormalities I have. My oncologist said a successful P-53 drug would be a "home run." She's working on one in her lab. Here's more about that mutation: https://ghr.nlm.nih.gov/gene/TP53

I think my insurance covered the test. At any rate no one has billed me for it.

Amy

09-03-2016, 07:13 AM	#4
Mtngrl Senior Member Join Date: May 2011 Location: Denver, CO Posts: 1,427	Re: Circulating tumor cells Joan-- My oncologist recommended the test that Guardant does. (http://guardanthealth.com/). It tests circulating tumor cells and identifies mutations and amplifications. My test showed three mutations and three amplifications. One of my amplifications is HER-2 (of course!). One of the mutations is P-53. There are drugs in phase 1 clinical trials for several of the abnormalities I have. My oncologist said a successful P-53 drug would be a "home run." She's working on one in her lab. Here's more about that mutation: https://ghr.nlm.nih.gov/gene/TP53 I think my insurance covered the test. At any rate no one has billed me for it. Amy