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Old 11-26-2014, 12:19 PM   #7
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rhondalea's Avatar
Join Date: Jun 2011
Location: Somerset, NJ
Posts: 487
Re: No Travel Required - KRAS-Variant Mutation and Breast Cancer

Well, I paid for the genotyping, so I have 900k individual results. That's how I know that Provigil won't work for me and that I shouldn't take Ritalin while I'm taking tamoxifen.

For the same reason, I knew in advance that I don't carry the KRAS-variant, although Joanne claims only her patented test can detect it. I simply don't have the SNP, so it's not an issue even if it were an issue, which it isn't based on the research to date.

I don't care about the backgrounds of the researchers. I do care about the manner in which they conduct their research. I care about their professional ethics. I want to know that they live up to their agreements in the context of their professional lives. What they're doing otherwise is not my business.

Computers are very useful for procrastination. On the other hand, I've been glued to the keyboard for 30 years, so it no longer feels like procrastination to me (even though I know that sometimes it absolutely is exactly that). Today, however, we have snow, so I feel justified in taking a day off and doing lazy things. Still have to clean the litter boxes, though. The cats won't allow me to slack on that.

2/6/09 Core needle biopsy: negative; Mammos through 2010: no change
3/30/11 Pea-sized lump in left breast at site of prior biopsy; mammo negative, sonogram not so much
4/14/11 Core needle biopsy: negative for cancer
5/18/11 Excisional biopsy 1.2 cm tumor, LVI, positive margin; ER+60%,PR+20%,HER2/CEP17 5
6/15/11 BMX: Left DCIS & LH; Right ADH; SNB: 2/3 nodes: 1.4 cm and 1 mm; ALND L1&2: 0/10; Stage IIa, Grade 3
7/14/11 CT/Bone scans NED; MUGA 66%
7/19/11 Biweekly dd AC w/Neulasta; done 8/30/11
9/13/11 Transfusion (Hemoglobin 8.6); MUGA 64%
9/20/11 Start Taxol + Herceptin; Taxol done 12/6/2011; continue Herceptin until 9/4/2012
12/27/11 Radiation - 6 weeks; 2/27/2012 - DONE! Yayyyy!
2/29/12 Start Tamoxifen 20 mg/day; continue until 2/28/17
5/16/12 Start five-years Metformin trial
6/19/12 MUGA 61%
8/21/12 Brain MRI NED (head still hurts, brain still fogged)
9/4/12 Herceptin done!
9/6/12 Port out!
7/11/13 Aricept 5mg for cognitive impairment; increased to 10mg as of 8/23/13; back to 5mg 12/2013
5/2014 Add Namenda 7mg
9/2014 Stop Aricept and Namenda; Neuropsychological evaluation
10/24/14 Start cognitive rehabilitation therapy
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