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Old 06-17-2021, 04:21 PM   #101
R.B.
Senior Member
 
Join Date: Mar 2006
Posts: 1,843
Re: Vitamin D thread -Please use this for your Vit D info.

Vitamin D 'derivative" calcifediol appears to significantly reduce COVID-10 ICU and mortality risk.

There is a huge amount of research suggesting vitamin D is central to immune function regulation.

Many observational studies point to low vitamin D increasing COVID-19 risks.

Why this information has not reached the main stream or been reported is really puzzling. As a result the necessary confirmatory research has not been done, and people are likley arguably dying unnecessarily.

"Do you know how many people Calcifediol has been able to save their lives in this pandemic?
We don't know the number, but we do know there have been thousands of covid patients around the world."


https://www.diariocordoba.com/cordob...-53335018.html

A group of us have been trying to highlight the likely effect of vitamin D insufficiency in COVID for well over a year but have very sadly failed to make much impact - to cheap and simple? - a hundred years research,side effects are very limited, part of our evolutionary physiology, a steroid like dexamethasone but largely ignored by the mainstream . . . .

Co-factors are also necessary - they include the minerals such as zinc and magnesium - B12 and iodine also have roles . . . as do other nutrients etc . . .

And this study "Epigenetic Factors Predicting More Severe COVID-19 Revealed "https://www.clinicalomics.com/topics/patient-care/coronavirus/epigenetic-factors-predicting-more-severe-covid-19-revealed/
evidences that epigenetics factors in COVID - of crucial importance diet is one of the major players in determining epigenetic switching on and off of gene function

A case of the Semmelweis Effect? The Doctor Who Championed Hand-Washing And Briefly Saved Lives https://www.npr.org/sections/health-...-women-s-lives





A recent published study


Calcifediol treatment and COVID-19-related outcomes

https://academic.oup.com/jcem/advanc...gab405/6294179




Conclusions

In patients hospitalized with COVID-19, calcifediol treatment significantly reduced ICU admission and mortality



"Main Outcome Measures

ICU admission and mortality.
Results

ICU assistance was required by 102 (12.2%) participants. Out of 447 patients treated with calcifediol at admission, 20 (4.5%) required ICU, compared to 82 (21%) out of 391 non-treated (p-value<0.0001). Logistic regression of calcifediol treatment on ICU admission, adjusted by age, gender, linearized 25OHD levels at baseline, and comorbidities showed that treated patients had a reduced risk to require ICU (OR 0.13 [95% CI 0.07;0.23]). Overall mortality was 10%. In the Intention-to-Treat analysis, 21 (4.7%) out of 447 patients treated with calcifediol at admission died compared to 62 patients (15.9%) out of 391 non-treated (p=0.0001). Adjusted results showed a reduced mortality risk with an OR 0.21 [95% CI 0.10; 0.43]). In the second analysis, the obtained OR was 0.52 [95% CI 0.27;0.99]."

Last edited by R.B.; 06-17-2021 at 04:49 PM..
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