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I was positive by IHC and weakly positive by FISH (40%). At Duke that meant no Herceptin for me. When I changed Onc's (wait at Duke was 2hours in office min.!) The Onc from Duke wrote my new Onc saying that Herceptin would be beneficial for me! Wow, I have been on Herceptin ever since. I guess there is no other safety net right now and there is so MUCH they don't really know. That's my experience for what little it's worth. Stage 3a - 7 nodes positive er+ pr weakly positive...
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