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Astrid
The 16% on your estrogen receptor does not correlate to the chance of DFS or overall survival or the chance that an antihormonal will work. It relates to how much staining for the estrogen receptor (ER) was present on the piece the pathologist tested for ER during testing. Yours stains 16%. I am 50% ER so mine stained more. The higher your ER and PR % the more you may respond to anti hormonal therapy. Therefore, someone like my mother (who is Her2 negative) should respond very well since she is 98% ER and 90% PR.
Many women on this board who are Her2+ are also strongly hormone positive like my mother as well.
Being hormone + and Her2+ is not rare in the Her2 world. About 45% - 50% of Her2+ women are also hormone positive as well which relates to your 15% figure of all bc overall (since 25% - 30% are Her2+ and half of that is about 15%).
I hope this clears up the % part of the hormone receptors. For the record, there are 3 rules of thought on being hormone negative.
1. Some experts say that if you are less than 10% ER or PR, then they consider that negative.
2. Some experts bring that number down to being less than 5% ER or PR then you are considered negative.
3. Some experts say if you can measure or stain anything at all (let's say 1%) they consider that positive.
In my research however (I am 50% ER but less than 5% PR so this topic greatly interests me), I am considered PR negative (and I have had 4 opinions from oncos on that and alot of literature stating that).
Kindest regards
Becky
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