HER2 Support Group Forums - View Single Post - Weekly versus 3 week Herceptin dose studies

heblaj01 · 07-17-2006, 11:55 AM

I would like to mention the remarkable repeated succes by Gina in regressing 4 times her liver mets over 4 years of interrupted & resumed Herceptin treatments at various doses escalated when necessary depending on the size or number of the mets.
She is attributing this repeated succes to the fact that the relatively high number of high initial loading doses increased the chances of suppressing more HER receptors.
If this is true then the every 3 week IV which is usually a higher dose than the weekly infusion may carry a small advantage in spite of the fact that over time the average dose is the same in the two regimen.
Of course all this is pure speculation not proven fact.

07-17-2006, 11:55 AM	#16
heblaj01 Senior Member Join Date: Apr 2006 Posts: 543	I would like to mention the remarkable repeated succes by Gina in regressing 4 times her liver mets over 4 years of interrupted & resumed Herceptin treatments at various doses escalated when necessary depending on the size or number of the mets. She is attributing this repeated succes to the fact that the relatively high number of high initial loading doses increased the chances of suppressing more HER receptors. If this is true then the every 3 week IV which is usually a higher dose than the weekly infusion may carry a small advantage in spite of the fact that over time the average dose is the same in the two regimen. Of course all this is pure speculation not proven fact.