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Chelee
Is your cancer on the left or the right? I really don't think the Herceptin dosing schedule is a big deal at all (1 wk versus 3 wks). But the comment on the rads and the heart makes some logical sense (although I have heard many times it doesn't matter at all and I started my first 15 as weeklies and switched but took everything separate (ie: surgery then chemo then rads then Herceptin).
Comment on left or right side - heart is on the left and depending on radiation field, could affect the heart if you need rads on the left (therefore, may want to play Herceptin safer by weeklies (if this is even true)). If on right, pick your timing.
Have a nice weekend.
Becky
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