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Herceptin and an anti hormonal are a great combination for a one-two punch. It does not matter if you are on an AI or tamoxifen. However, once the Herceptin year (or two) is over, one still has to stay on the antihormonal for a total of 5 years. That is when the dilemna comes in if you are on Tamoxifen versus an AI. Tamoxifen may not work well for those who are also Her2+ (especially if you are only moderately hormone positive. For example, I am 50% ER but PR neg. The literature says that I am not a good tamoxifen candidate. However, tamoxifen may work for some Her2+ patients).
An AI without Herceptin is always a good bet and works best for Her2+ patients (and works best for Her2 neg patients too - AIs have just been proven, over and over again, to be better than tamoxifen - but you have to be postmenopausal to take them). Hence, I had an oophorectomy to take them.
Kind regards
Becky
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