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I was told that estrogen status was a mechanism that either goes one way or the other in the early stages of the cancer development. I had both ER+ and ER- bilateral breast cancer. I kept scratching my head wondering which kind of treatment they would recommend for me. But since the ER- bc was IDC and the ER+ was DCIS, I got the ovaries removed instead of getting any of the estrogen blockers. Also, they mentioned that the ER- cancer tended to "find a way" to survive without the presence of estrogen.
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