HER2 Support Group Forums - View Single Post

heblaj01 · 07-03-2006, 01:42 PM

While on Herceptin alone, this elderly lady in my family had the following monthly CEA readings:
129 just before starting on Herceptin (highest reading ever)
102
75
98

The sudden reversal from a monthly average decrease of 20% to a 30% increase is quite worrysome if it means resistance to Herceptin.

Has anyone experienced such sharp reversals in CEA or other markers & still continued to benefit from Herceptin?
Or was the trend in markers continuously down?

She was found HER+ ER- in april 2006 (after being ER+ for over more than 20 years)

07-03-2006, 01:42 PM	#1
heblaj01 Senior Member Join Date: Apr 2006 Posts: 543	Marker ups & downs on Herceptin alone? While on Herceptin alone, this elderly lady in my family had the following monthly CEA readings: 129 just before starting on Herceptin (highest reading ever) 102 75 98 The sudden reversal from a monthly average decrease of 20% to a 30% increase is quite worrysome if it means resistance to Herceptin. Has anyone experienced such sharp reversals in CEA or other markers & still continued to benefit from Herceptin? Or was the trend in markers continuously down? She was found HER+ ER- in april 2006 (after being ER+ for over more than 20 years)