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06-25-2006, 11:53 PM

I wondered the same--and have been taking Arimidex at bedtime over the past 4 years and so far so good--dx'd 3/01 w/3 to 4 different types of very aggressive b.c. (pleomorphic invasive lobular, rare presentation of IBC (in nipple only w/Pagetian spread), and high grade dcis with extensive comedo necrosis), er+, her2+, 9 of 12 pos. nodes not matted together (but first CT scan report indicated that there appeared to be remaining lymph nodes that WERE matted together, elevated tumor markers, extensive lymphovascular invasion, and extracapsular spread.
Tx--bilateral mastectomy, chemo (4 AC), rads (25 treatments w/out boost), more chemo--2 Taxol and 2 Taxotere w/weekly Herceptin starting w/first taxane--for 1 year, followed by complete hysterectomy/oopherectomy. Other treatments--beta seron (for m.s. for past 11 yrs), Doxycycline and Celebrex--started after hysterectomy (a few mos. after becoming hypothyroid)--Celebrex -- initially 100 mg--twice/day, then after a month or two it was increased to 200 mg/twice/day, then 9 mos. later it was increased to 400 mg/twice/day and Lovastatin was added.

06-25-2006, 11:53 PM	#4
Kaye301 Guest Posts: n/a	timing of medication I wondered the same--and have been taking Arimidex at bedtime over the past 4 years and so far so good--dx'd 3/01 w/3 to 4 different types of very aggressive b.c. (pleomorphic invasive lobular, rare presentation of IBC (in nipple only w/Pagetian spread), and high grade dcis with extensive comedo necrosis), er+, her2+, 9 of 12 pos. nodes not matted together (but first CT scan report indicated that there appeared to be remaining lymph nodes that WERE matted together, elevated tumor markers, extensive lymphovascular invasion, and extracapsular spread. Tx--bilateral mastectomy, chemo (4 AC), rads (25 treatments w/out boost), more chemo--2 Taxol and 2 Taxotere w/weekly Herceptin starting w/first taxane--for 1 year, followed by complete hysterectomy/oopherectomy. Other treatments--beta seron (for m.s. for past 11 yrs), Doxycycline and Celebrex--started after hysterectomy (a few mos. after becoming hypothyroid)--Celebrex -- initially 100 mg--twice/day, then after a month or two it was increased to 200 mg/twice/day, then 9 mos. later it was increased to 400 mg/twice/day and Lovastatin was added.