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astrid · 06-12-2006, 07:10 AM

Check your pathology report. My tumor was 2+ with an IHC or immunohistochemistry. My FISH test was 3.4. I am ER+, PR+. Most Her2+ BC are ER-. So triple + (ER+, PR+ and HER2+) is only 15% of all BCs. If your FISH and IHC are only 2+ this is borderline and Herceptin may not have any benefits.

06-12-2006, 07:10 AM	#8
astrid Senior Member Join Date: Jun 2006 Location: Central North Carolina, USA Posts: 112	Check your pathology report. My tumor was 2+ with an IHC or immunohistochemistry. My FISH test was 3.4. I am ER+, PR+. Most Her2+ BC are ER-. So triple + (ER+, PR+ and HER2+) is only 15% of all BCs. If your FISH and IHC are only 2+ this is borderline and Herceptin may not have any benefits.