Thread: PTEN positive
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Old 06-11-2006, 09:23 PM   #2
heblaj01
Senior Member
 
Join Date: Apr 2006
Posts: 543
Gina,

Your case is always full of unexpected & seemingly conflicting conditions which are resolving themselves fortunately into favorable outcomes.
Are you the one in a million lucky one?
Or is there something to be learned from your travails that might be usefull to others?
I am referring first to your statement in the above post in this thread that you were initially found to be highly positive for both EGFR & HER.
Second, this not only did not make you resistant to Herceptin (as a single drug treatment) but even let you stop & start 4 times the treatment, each time succeeding in regressing liver mets over about 4 years!

I know you attribute the regressions to the higher than normal number of heavy loading doses . But how do you explain the absence of resistance in the face of high EFGR?

Were EFGR & HER levels checked only once? Could they be changing over time?
Any personal opinion or comment from your onc?
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