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Just wanted to add my concerns about the high dose of Xeloda. Two years ago my Onc put me on 4300mg per day. I am 5'8" and about 145lbs. Within 10 days I was a very sick girl, with high fever, diarrhea, etc. I spent a week in the hospital on four different antibiotics, required 2 units of blood, and a unit of plasma. I was as sick as when I had my stem cell procedure back in 97. My Onc said that it was probably something peculiar to me that I wasn't able to metabolize the drug and it built up to very toxic levels. He said I would never be able to use Xeloda again, but I really have to wonder in view of all the new evidence. Maybe I would have done fine on a smaller dose. I really hate the idea that I can't use Xeloda, if I ever need it, because I know it has worked so well for many.
Kim in CA
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