lu ann-
I've been on xeloda for almost a year, as part of a clinical trial. My original dosage was 2500/mg2, which for my weight was 2150 mg every 12 hours. I was fine the first 2 cycles (6 weeks) then got horrible H/F/diarrhea/rash and every other symptom you coud imagine...dosage was reduced 25%, which for my weight is 1650mg every 12 hours. I shorten a cycle if the H/F seems to be exacerbating things, and most of the other symptoms are resolved...
Personally, I'd like to go to 11 days on and 10 days off, but the trial has not approved that regimen...
Two months ago, lapatinib (tykerb) was added to my regime, and I get a CT scan tomorrow - hoping for incredible results!!
Hang in there - and check out the
www.xeloda.com website which answers a lot of questions...
Shell