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Lolly · 05-29-2006, 08:34 AM

Chelee, I don't know the answer to your original question, but being positive or negative for ER/PR has no bearing on whether you qualify for Herceptin; they look only at the HER2 factor. I am ER/PR negative and my latest FISH score was amplified at 4.6+ as I remember. There are normally 2 copies of each gene, and so the test showed that I have more than 4 copies of the HER2-neu gene per cell, as do you.

05-29-2006, 08:34 AM	#5
Lolly Senior Member Join Date: Aug 2001 Location: Oregon Posts: 1,756	Chelee, I don't know the answer to your original question, but being positive or negative for ER/PR has no bearing on whether you qualify for Herceptin; they look only at the HER2 factor. I am ER/PR negative and my latest FISH score was amplified at 4.6+ as I remember. There are normally 2 copies of each gene, and so the test showed that I have more than 4 copies of the HER2-neu gene per cell, as do you.