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Question.
What is it about chemo that is claimed to activate tumours to herceptin?
How long does the effect of chemo continue after completion of administration (washout)?
If herceptin is reliant on chemo and chemo washes out what is the logic of long term herceptin if it will not work without chemo?
Why should chemo impact on the reported ability of Herceptin to block FAS pathways which is recognised as a having significant in vivo anti tumour effect ( and herceptin may also work at other levels)?
So many questions.
RB
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