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I have not looked at the way chemo agents work.
But Herceptin is reported in papers to block FAS.
Fas blockers are reported as having significant in vivo antitumour activity in BC.
IF Fas blocking by Herceptin is body wide (and there is evidence of expression if not over expression of HER2 in other areas of the body e.g. arthritis) and if applicable to all longer chain fatty acid production in whole or in part it would reduce DHA production. (the body can make dha from linolenic acid omega three, as it does arachidonic acid AA a percusor of COX 2 from linoleic omega six - shutting down AA might well be good news in a body that is awash with omega six, but shutting down omega three in the absence of supplementation may have negative impact (and may increase with time ???) as DHA etc is essential to human health, particularly brain and eyes.
In pregnant women it is suggested that the developing foetus is capable of drawing down DHA from the bodies likley largest source of DHA - so in people with low DHA synthesys and low intake could the body be robbing the brain to keep other things going and how long is that an option before the impact on the brain of low DHA manifests.
Smart Fats by A Scmidt cites trials which suggest brain tumours have high omega and low DHA.
Statistics show DHA consumption has dropped dramatically and inflamatory omega sixes increased.
Lack of DHA in the brain has been linked at various levels to a number of brain disorders and general lack of cognitive process.
IF a consequence of treatment is blocking disrupting fatty acid sythesys pathways the body would have to rely on ingested sources.
Conclusion - there are a lot of potential upsides to Fish oil, algae, DHA supplementation and few evident downsides.
AND trials suggest that adequate omega three intake reduces the risk of BC.
I do not have the answers I am just raising questions based on papers I have been reading - images in the fog.
As ever please discuss dietary changes with your advisors.
RB
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