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For statistics on hormone driven cancer (general info - not necessarily combined with Her 2 status), the first 2 years are the greatest chance of recurrence (much like hormone negative cancer's rate of recurrence) however, hormone driven cancer also has the same (higher) rate of recurrence between 7-9 years out as well. Hormone negative cancer does not have this repeat blip. I do feel this is from the supressive effect of tamoxifen (since this is older data and AI's have not been in use that long). Preliminary data collaberates that AIs will reduce all rates of recurrence in hormone driven cancer.
For the record, I am (of course) Her 2+ but ER + and PR-. I got my ovaries removed in order to use Arimidex since Jen is correct that AIs do work better for ER+ and PR- (than tamoxifen in this pathology group). Since I was still premenopausal, this was just one of the reasons I had my ovaries removed as Herceptin with an AI made the most sense for me (ovarian cancer also runs in the family so I had multiple reasons).
Kind regards
Becky
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