HER2 Support Group Forums - View Single Post - interim results of Canadian clinical trial w pegylated doxorubicin and herceptin

heblaj01 · 05-13-2006, 07:25 AM

If the results of this trial are confirmed in a phase 3 trial with a much larger number of patients I believe that it will mean a big improvement over the results of chemo+herceptin phase 3 trials reported at the end of 2005.

The reason for this lies in the way the statistics were reported in 2005.
The 50% reduction in recurrence rate was a relative figure not an absolute figure. The absolute figure was much lower.

The important statistic to watch, beside quality of life, is overall survival duration (more significant than disease free survival without longer life expectancy)

05-13-2006, 07:25 AM	#4
heblaj01 Senior Member Join Date: Apr 2006 Posts: 543	interim results of Canadian clinical trial w pegylated doxorubicin and herceptin If the results of this trial are confirmed in a phase 3 trial with a much larger number of patients I believe that it will mean a big improvement over the results of chemo+herceptin phase 3 trials reported at the end of 2005. The reason for this lies in the way the statistics were reported in 2005. The 50% reduction in recurrence rate was a relative figure not an absolute figure. The absolute figure was much lower. The important statistic to watch, beside quality of life, is overall survival duration (more significant than disease free survival without longer life expectancy) Last edited by heblaj01; 05-13-2006 at 07:34 AM..