HER2 Support Group Forums - View Single Post - for Jean and others-Topo2a identifies those patients needing anthracylines

al from Canada · 05-10-2006, 11:47 PM

TOPO II testing is relatively new and therefore most oncs will not be aware of it, unless they go to conferences as we do. That said, the TOPO II test is also a predictor of who might suffer LVF problems in the future which is probably even a better reason for having that test. If my memory serves me well, the TOPO II test may also be used as a predictor of who will respond favourably to herceptin without cardio problems therefore may be used by some countries in a herceptin cost / benefit analysis. Dr. Slaman mentioned that this can be done with the FISH therefore needent be costly. When I talked to our onc last Dec. he hadn't heard of the marker.

I would be interested in how many members or their oncs are aware of this test.

Al

05-10-2006, 11:47 PM	#3
al from Canada Senior Member Join Date: Jul 2005 Location: Ontario, Canada Posts: 722	TOPO II testing TOPO II testing is relatively new and therefore most oncs will not be aware of it, unless they go to conferences as we do. That said, the TOPO II test is also a predictor of who might suffer LVF problems in the future which is probably even a better reason for having that test. If my memory serves me well, the TOPO II test may also be used as a predictor of who will respond favourably to herceptin without cardio problems therefore may be used by some countries in a herceptin cost / benefit analysis. Dr. Slaman mentioned that this can be done with the FISH therefore needent be costly. When I talked to our onc last Dec. he hadn't heard of the marker. I would be interested in how many members or their oncs are aware of this test. Al __________________ Primary care-giver to and advocate for Linda, who passed away April 27, 2006.