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Irene,
I was only on Herceptin for 1 year but I had muscle cramps in my legs and back that started while on Herceptin. I never had spasms prior to that. They decreased somewhat when I stopped the Herceptin but I do still get them 3 1/2 years later. They became so annoying during the night that I now take a muscle relaxant prior to going to bed. I had wondered if my salt or potassium levels were off but everything checked out ok. My onc isn't sure that the cause of the spasms is the Herceptin but I believe it is.
Sue
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