HER2 Support Group Forums - View Single Post - Docetaxel, cisplatin, and trastuzumab show great result

Christine MH-UK · 05-05-2006, 03:35 PM

Hi kk1,

I read through the article and it seems like there was no year of herceptin given at the end. The cost accountants will love this one (I told a chemo nurse about it today and her reaction was basically, "good, no new drugs are involved").

Of course, the big concern is cardiotoxicity. According to the article "Eighteen patients refused postadjuvant chemotherapy MUGA scans because they were asymptomatic. Of the remaining 30 patients, 14 patients’ ejection fractions remained normal, whereas 10 patients (33%) had grade 1 cardiotoxicity, and six patients (20%) had grade 2 cardiotoxicity." What I don't know is whether that is good or bad.

05-05-2006, 03:35 PM	#9
Christine MH-UK Senior Member Join Date: Sep 2005 Posts: 414	Great stuff Hi kk1, I read through the article and it seems like there was no year of herceptin given at the end. The cost accountants will love this one (I told a chemo nurse about it today and her reaction was basically, "good, no new drugs are involved"). Of course, the big concern is cardiotoxicity. According to the article "Eighteen patients refused postadjuvant chemotherapy MUGA scans because they were asymptomatic. Of the remaining 30 patients, 14 patients’ ejection fractions remained normal, whereas 10 patients (33%) had grade 1 cardiotoxicity, and six patients (20%) had grade 2 cardiotoxicity." What I don't know is whether that is good or bad.