|
JoJo;
Platinum agents, carboplatin (Paraplatin) or (less commonly) cisplatin (Platinol). At this time carboplatin is preferred over cisplatin in the combination because studies indicate that carboplatin is as effective as cisplatin but is less toxic and can be administered in a more convenient, outpatient regimen.
Taxanes, paclitaxel (Taxol) and docetaxel (Taxotere). Taxol was the first taxane develped and brought to market. The more recent synthetic version Taxotere has been showing improved efficacy so is gaining ground as the standard of care over the more traditional Taxol. Now we very recntly also have Abraxane which is just Taxol/paclitaxel packaged in little nanoparticles so it causes less side effects than Taxol, so can be given in high doses, and out performed Taxol in recent pahse III studies. At this point I have not seen any studies comparing Abraxane with Taxotere so who knows where the standard of care will go next.
KK1
|