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Underdose
My wife's Onc was the UK head of the HERA trial. Half way through treatment we went on an extended holiday and he seemed quite calm about missing a session or extending the gaps as he explained Herceptin has a long half life - so the underdose may not be a cause for undue alarm.
The higher dose on the next visit or bringing the session forward a week sounds like a good idea.
John L
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