HER2 Support Group Forums - View Single Post - HER2/neu+ and ER+ post treatment question

Tricia L. · 04-26-2006, 08:41 PM

I have just finished my radiation treatments and was ready to begin Tamoxifen until I read an article about a study being done on HER2+ and ER+ patients that says Tamoxifen may act like estrogen in these patients, acting like a growth factor. I have talked with my oncologist about treatment route and one way would be to remove my ovaries which would put me into a post-menopausal state and then I could take one of the aromatase inhibitors. Anyone familiar with this study? I know it is being done at Baylor University and is now just in clinical trials. Any thoughts pros and cons on ovary removal, etc... I am 45 years old. I had a lumpectomy and node negative.

04-26-2006, 08:41 PM	#1
Tricia L. Junior Member Join Date: Apr 2006 Location: Birmingham, Alabama Posts: 4	HER2/neu+ and ER+ post treatment question I have just finished my radiation treatments and was ready to begin Tamoxifen until I read an article about a study being done on HER2+ and ER+ patients that says Tamoxifen may act like estrogen in these patients, acting like a growth factor. I have talked with my oncologist about treatment route and one way would be to remove my ovaries which would put me into a post-menopausal state and then I could take one of the aromatase inhibitors. Anyone familiar with this study? I know it is being done at Baylor University and is now just in clinical trials. Any thoughts pros and cons on ovary removal, etc... I am 45 years old. I had a lumpectomy and node negative.