I have been on weekly Herceptin. At one time, my ankles were swollen, but not discolored nor tingly. I was on a vacation, so I did a lot of walking. I thought that I walked too much that it caused the swelling. Then I saw my onc nurse, she prescribed me a "water pill" due to poor circulation. She said that my heart was not pumping strongly enough. I was off Herceptin for a couple of weeks, until I passed yet another Echo exam. Kansasrose, this may be your situation. I ditto everyone's posts, since you haven't seen an onc for a good while, it's high time you saw one again. Have your ankles checked out soon! God bless.
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